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Semaglutide Dose Calculator: Convert a Prescribed mg Dose to mL and Insulin-Syringe Units From Your Vial Concentration

A conversion check for compounded semaglutide vials: enter the prescribed dose and the mg/mL concentration on your label to see the volume in mL and units on a U-100 syringe. A check on your pharmacist's instructions, not a substitute for them.

Enter the prescribed dose and the concentration printed on your vial label.

Why a conversion tool exists

FDA-approved Wegovy comes in pens that deliver a fixed dose. Compounded semaglutide comes in a multi-dose vial, and the patient draws up each dose with an insulin syringe marked in units. Units measure volume — 100 units is 1 mL on a U-100 syringe — and the amount of drug in a given volume depends on the concentration the pharmacy used, which varies from vial to vial and pharmacy to pharmacy. The FDA has received reports of patients taking five, ten and twenty times the intended dose after confusing units with milligrams or using a units figure meant for a different concentration. This tool exists to catch that error.

How to use it

Find the concentration on your vial label, written as mg/mL (for example 2.5 mg/mL or 5 mg/mL). Enter it with the dose your clinician prescribed. The result is the volume in mL and the equivalent units. Compare it with your pharmacy's written instructions. If they differ, do not inject; call the pharmacy. If your label does not state a concentration, do not inject; ask for it in writing.

What the tool will not do

It will not suggest a dose, escalate a dose, or convert between semaglutide products. The labeled Wegovy schedule is shown for reference only. See semaglutide units vs milligrams for the full explanation.

Frequently asked questions

How many units is 0.25 mg of semaglutide?

It depends entirely on the vial concentration. At 2.5 mg/mL, 0.25 mg is 0.1 mL, which is 10 units on a U-100 insulin syringe. At 5 mg/mL it is 5 units. Never use a units figure from someone else's vial.

Does this calculator choose my dose?

No. Your clinician chooses the dose; this tool converts it to a volume using the concentration on your label. If the result differs from your pharmacy's instructions, call the pharmacy before injecting.

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